The ingredients that actually repel bugs
A short list does the heavy lifting. EPA-registered synthetic actives like DEET and picaridin have decades of efficacy review behind them; minimum-risk botanicals like citronella and cedarwood oil skip that review but show up in plenty of “natural” sprays. Here’s every ingredient we actually evaluate, with the safety and evidence that matters.
Look up any EPA-registered chemical →
162 ingredients
DEET
N,N-Diethyl-meta-toluamide
Yes. DEET is the most-studied insect repellent ever made, with six decades of evidence behind it. It confuses the receptors mosquitoes use to find you, and at 25% it delivers roughly 4–5 hours of complete protection. Its real drawbacks are feel, odor, and its appetite for plastics. Safety is not one of them; it is well established at normal use.
Water
Water as disclosed on the product label.
Lemongrass oil
Oils, lemongrass
Yes. Lemongrass is among the stronger essential-oil repellents, with complete protection around an hour to ninety minutes at well-formulated concentrations. That's the top of the botanical class, and still a fraction of any synthetic.
Cedarwood oil
Oils, cedarwood
Against mosquitoes, the evidence is minimal. Against ticks, there's a genuine signal: cedrol, a cedarwood component, measurably repels ticks for short windows. Treat cedarwood products as brief, tick-leaning helpers, not mosquito protection.
Oil of Lemon Eucalyptus
p-Menthane-3,8-diol (PMD) — primary active in refined OLE
Yes. It's the only plant-derived active with synthetic-class performance. Refined to 30% (standardized for PMD, its active molecule), it delivers 4–6 hours of complete mosquito protection. Two honest caveats: it underperforms against ticks, and it's not for children under 3.
Picaridin
Icaridin (2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester)
At 20%, picaridin matches or beats DEET in head-to-head field trials: 8–12 hours of complete mosquito protection and 7–8 hours against ticks, all without the odor, greasy feel, or plastic damage. It's why picaridin products top our rankings.
Citronella oil
Oils, citronella
Barely, and briefly. Citronella is the most famous botanical repellent and one of the weakest performers in controlled testing, lasting under 20 minutes of complete protection in the landmark NEJM study. It repels mosquitoes; it just stops doing so almost immediately.
Peppermint oil
Botanical oil from Mentha piperita used in minimum-risk repellent formulations.
Rosemary oil
Oils, rosemary
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Geraniol
2,6-Octadien-1-ol, 3,7-dimethyl-, (2E)-
Yes, and at the right concentration, better than most botanicals. Luker 2023 arm-in-cage tests found 10% geraniol in a lotion emulsion protected for over 60 minutes against both mosquitoes and ticks. López 2025 showed the dose-response has a steep cliff: below 4% it's nearly useless, but at 5% it reaches the same plateau as 10%. Products with 5%+ geraniol in a lotion base deserve a serious look; products at 1–3% do not.
Geranium oil
Oils, geranium
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
IR3535
3-(N-Butyl-N-acetyl)aminopropionic acid, ethyl ester
IR3535 is a synthetic amino-acid derivative that's been Europe's quiet workhorse repellent for over 30 years. At 20% it provides roughly 6–8 hours against both mosquitoes and ticks, with one of the gentlest safety profiles of any synthetic.
Clove oil
Oils, clove
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Glycerin
1,2,3-Propanetriol
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Fragrance
Fragrance as disclosed on the product label.
Ethanol
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Proprietary essential oil blend (undisclosed)
Undisclosed proprietary blend of essential oils used as the repellent-active component; the manufacturer does not publish the specific oils or percentages.
Vitamin E
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Castor oil
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Organic non-GMO sugarcane alcohol
Organic non-GMO sugarcane alcohol as disclosed on the product label.
Soybean oil
Plant oil used as an active ingredient in minimum-risk insect repellent formulations.
Aloe barbadensis extract
Aloe barbadensis extract as disclosed on the product label.
Thyme oil
Oils, thyme
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
p-Menthane-3,8-diol
Cyclohexanemethanol, 2-hydroxy-.alpha.,.alpha.,4-trimethyl-
PMD is the active molecule inside oil of lemon eucalyptus, and the only plant-derived repellent compound with DEET-class evidence. At 30%-OLE-equivalent concentrations it provides 4–6 hours of complete mosquito protection.
Citric acid
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Cinnamon oil
Botanical oil used in minimum-risk tick and insect repellent formulations.
Eucalyptus Citriodora Oil (Lemon eucalyptus oil)
Eucalyptus Citriodora Oil (Lemon eucalyptus oil) as disclosed on the product label.
Hexylene glycol
2,4-Pentanediol, 2-methyl-
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Oils, catnip
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
SD Alcohol 40-B
SD Alcohol 40-B as disclosed on the product label.
Sodium benzoate
Benzoic acid, sodium salt
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Vanillin
Benzaldehyde, 4-hydroxy-3-methoxy-
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Lavender oil
Oils, lavender
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Beeswax
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Extra virgin olive oil (organic)
Extra virgin olive oil (organic) as disclosed on the product label.
Juniper berry oil
Juniper berry oil as disclosed on the product label.
Octinoxate
Octinoxate as disclosed on the product label.
Octisalate
Octisalate as disclosed on the product label.
Polyurethane copolymer
Polyurethane copolymer as disclosed on the product label.
Potassium sorbate
Sorbic acid, potassium salt
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Stearic acid
Octadecanoic acid
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Acrylates/octylacrylamide copolymer
Acrylates/octylacrylamide copolymer as disclosed on the product label.
Chamomile oil
Chamomile oil as disclosed on the product label.
Eugenol
Phenol, 2-methoxy-4-(2-propen-1-yl)-
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Glyceryl stearate
Octadecanoic acid, ester with 1,2,3-propanetriol
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Isopropanol
2-Propanol
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Isopropyl myristate
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Jojoba (Simmondsia chinensis) Oil
Jojoba (Simmondsia chinensis) Oil as disclosed on the product label.
Lecithins
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Methyl nonyl ketone
2-Undecanone
2-Undecanone (methyl nonyl ketone) is a biochemical repellent active derived from wild tomato plants (Lycopersicon hirsutum), where it serves as a natural defense against insects. It also occurs naturally in bananas, cloves, ginger, and guava. Registered by the EPA as a biochemical pesticide, it was the first new repellent active ingredient approved in over 25 years and is used in DEET-free formulas against mosquitoes and ticks.
Octocrylene
Octocrylene as disclosed on the product label.
Oxybenzone
Oxybenzone as disclosed on the product label.
Polyethylene glycol
Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Propylene glycol
1,2-Propanediol
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Sunflower (Helianthus annuus) Seed Oil
Sunflower (Helianthus annuus) Seed Oil as disclosed on the product label.
Xanthan gum
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Chamomile (Chamomilla recutita) Flower Extract
Chamomile (Chamomilla recutita) Flower Extract as disclosed on the product label.
Coconut oil
Coconut oil as disclosed on the product label.
Dipropylene glycol monomethyl ether
Propanol, 1(or 2)-(2-methoxymethylethoxy)-
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Eucalyptus oil
Oils, eucalyptus
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Fir Needle (Abies siberica) Oil
Fir Needle (Abies siberica) Oil as disclosed on the product label.
Isobutane
Propane, 2-methyl-
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Isopropyl alcohol
2-Propanol
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Lauric acid
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Propane
Propane as disclosed on the product label.
Soya lecithins
Lecithins, soya
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
1,2-Hexanediol
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Alcohol
Alcohol as disclosed on the product label.
Alcohol Denat.
Alcohol Denat. as disclosed on the product label.
Almond oil
Oils, almond
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Aloe barbadensis leaf oil
Aloe barbadensis leaf oil as disclosed on the product label.
Aluminum magnesium silicate
Silicic acid, aluminum magnesium salt
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Ambrette (Hibiscus abelmoschus) Seed Oil
Ambrette (Hibiscus abelmoschus) Seed Oil as disclosed on the product label.
Andiroba seed oil
Andiroba seed oil as disclosed on the product label.
Apple Cider Vinegar (Acetic Acid)
Apple Cider Vinegar (Acetic Acid) as disclosed on the product label.
Apricot (Prunus armeniaca) Kernel Oil
Apricot (Prunus armeniaca) Kernel Oil as disclosed on the product label.
Arginine
Arginine as disclosed on the product label.
Avobenzone
Avobenzone as disclosed on the product label.
Avocado (Persea gratissima) Oil
Avocado (Persea gratissima) Oil as disclosed on the product label.
Barium sulfate
Sulfuric acid, barium salt (1:1)
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Bentonite
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Benzyl alcohol
Benzenemethanol
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Blue tansy flower/leaf/stem oil
Blue tansy flower/leaf/stem oil as disclosed on the product label.
Buddha Wood (Eremophila mitchellii) Oil
Buddha Wood (Eremophila mitchellii) Oil as disclosed on the product label.
Butylene glycol
Butylene glycol as disclosed on the product label.
C12-15 alkyl benzoate
C12-15 alkyl benzoate as disclosed on the product label.
C12-20 Alkyl Glucoside
C12-20 Alkyl Glucoside as disclosed on the product label.
C14-22 Alcohol
C14-22 Alcohol as disclosed on the product label.
Calcium benzoate
Benzoic acid, calcium salt
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Calendula (Calendula officinalis) Flower Extract
Calendula (Calendula officinalis) Flower Extract as disclosed on the product label.
Caprylhydroxamic acid
Caprylhydroxamic acid as disclosed on the product label.
Caprylic/Capric Triglycerides
Caprylic/Capric Triglycerides as disclosed on the product label.
Carbomer (Carbopol)
Carbomer (Carbopol) as disclosed on the product label.
Carnauba wax
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Cellulose
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Cetyl alcohol
Cetyl alcohol as disclosed on the product label.
Chlorophyllin-copper complex
Chlorophyllin-copper complex as disclosed on the product label.
Citral
2,6-Octadienal, 3,7-dimethyl-
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Citronellol
6-Octen-1-ol, 3,7-dimethyl-
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Clary Sage (Salvia sclarea) Oil
Clary Sage (Salvia sclarea) Oil as disclosed on the product label.
Cocoa
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Corn oil
Plant-derived carrier/active oil used in some FIFRA 25(b) minimum-risk botanical repellents. On the EPA 25(b) exempt active list.
Cornmint oil
Oils, mint, Mentha arvensis piperascens
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Cornstarch
Cornstarch as disclosed on the product label.
DEA-oleth-3 phosphate
DEA-oleth-3 phosphate as disclosed on the product label.
Diglycol/CHDM/isophthalates/SIP copolymer
Diglycol/CHDM/isophthalates/SIP copolymer as disclosed on the product label.
Dimethicone
Dimethicone as disclosed on the product label.
Disodium EDTA
Disodium EDTA as disclosed on the product label.
Farnesol
2,6,10-Dodecatrien-1-ol, 3,7,11-trimethyl-
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Flaxseed seed oil
Flaxseed seed oil as disclosed on the product label.
Glyceryl monostearate
Octadecanoic acid, monoester with 1,2,3-propanetriol
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Hemp (Cannabis sativa) Seed Oil
Hemp (Cannabis sativa) Seed Oil as disclosed on the product label.
Hinoki (Chamaecyparis obtusa) Wood Oil
Hinoki (Chamaecyparis obtusa) Wood Oil as disclosed on the product label.
Homosalate
Homosalate as disclosed on the product label.
Hydrogenated castor oil
Castor oil, hydrogenated
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Hydroxypropyl methyl cellulose
Cellulose, 2-hydroxypropyl methyl ether
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Hydroxypropyl Methylcellulose
Hydroxypropyl Methylcellulose as disclosed on the product label.
Imidazolidinyl urea
Imidazolidinyl urea as disclosed on the product label.
Isostearic acid
Isostearic acid as disclosed on the product label.
Lavender (Lavandula angustifolia) Hydrosol
Lavender (Lavandula angustifolia) Hydrosol as disclosed on the product label.
Lavender flower water
Lavender flower water as disclosed on the product label.
Lemon peel oil
Oils, essential, lemon
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Lime
Lime as disclosed on the product label.
Limonene
Cyclohexene, 1-methyl-4-(1-methylethenyl)-
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Linalool
Linalool as disclosed on the product label.
Magnesium aluminum silicate
Magnesium aluminum silicate as disclosed on the product label.
Myristic acid
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Neem oil
Fats and Glyceridic oils, margosa
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Octyl methoxycinnamate
Octyl methoxycinnamate as disclosed on the product label.
Palmitic acid
Hexadecanoic acid
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Palo Santo (Bursera graveolens) Wood Oil
Palo Santo (Bursera graveolens) Wood Oil as disclosed on the product label.
Patchouli (Pogostemon cablin) Leaf Oil
Patchouli (Pogostemon cablin) Leaf Oil as disclosed on the product label.
PEG/PPG-20/15 Dimethicone
PEG/PPG-20/15 Dimethicone as disclosed on the product label.
Polyglyceryl oleate
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Polyurethane-1
Polyurethane-1 as disclosed on the product label.
Potassium oleate
9-Octadecenoic acid (9Z)-, potassium salt
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Potassium stearate
Octadecanoic acid, potassium salt
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Propanediol
Propanediol as disclosed on the product label.
Propylene glycol myristyl ether acetate
Propylene glycol myristyl ether acetate as disclosed on the product label.
Quillaja saponaria extract (soap bark)
Quillaja saponaria extract (soap bark) as disclosed on the product label.
Rosemary (Rosmarinus officinalis) Extract
Rosemary (Rosmarinus officinalis) Extract as disclosed on the product label.
Safflower Oil
Safflower Oil as disclosed on the product label.
SD Alcohol 40
SD Alcohol 40 as disclosed on the product label.
Sesame oil
Fats and Glyceridic oils, sesame
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Soap
Soap (The water soluble sodium or potassium salts of fatty acids produced by either the saponification of fats and oils, or the neutralization of fatty acid)
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Sodium bicarbonate
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Sodium chloride
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Sodium citrate
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Sodium Gluconate
Sodium Gluconate as disclosed on the product label.
Sodium hydroxide
Sodium hydroxide (Na(OH))
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Sodium lauryl sulfate
Sulfuric acid monododecyl ester sodium salt (1:1)
EPA Substance Registry Services (SRS) listed active ingredient for pesticide products.
Spinach leaf extract
Spinach leaf extract as disclosed on the product label.
Sweet Almond (Prunus amygdalus dulcis) Oil
Sweet Almond (Prunus amygdalus dulcis) Oil as disclosed on the product label.
Tamanu seed oil
Tamanu seed oil as disclosed on the product label.
Triethyl citrate
Citric acid, triethyl ester
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Vanilla Planifolia Oleoresin
Vanilla Planifolia Oleoresin as disclosed on the product label.
Vegan Wax
Vegan Wax as disclosed on the product label.
Vetiver (Vetiveria zizanioides) Root Oil
Vetiver (Vetiveria zizanioides) Root Oil as disclosed on the product label.
VP/Eicosene copolymer
VP/Eicosene copolymer as disclosed on the product label.
Wintergreen oil
Listed as an inert ingredient permitted in EPA minimum risk (FIFRA 25(b)) pesticide products.
Witch Hazel (Hamamelis virginiana) Distillate
Witch Hazel (Hamamelis virginiana) Distillate as disclosed on the product label.
Witch hazel water
Witch hazel water as disclosed on the product label.