Meperfluthrin

Active

Meperfluthrin is a volatile synthetic pyrethroid used in mosquito mats, coils, and heated emanators. It vaporizes readily at warm temperatures to create a spatial repellent zone.

How it works

Like other pyrethroids it disrupts insect nerve-cell sodium channels; as a volatile active it works in the vapor phase, repelling and knocking down mosquitoes in the air around the device rather than on skin.

The evidence

Laboratory vapor-toxicity and knockdown studies place meperfluthrin among the more potent volatile pyrethroids against Aedes and Culex, but its independent, internationally regulated evidence base is thin: most efficacy data are lab knockdown comparisons, and safety data are limited to a small acute study and case reports flagging an inhalation and mucosal hazard at high exposure. It is not covered by WHO or EPA registration the way established actives are.

Knockdown and insecticidal activities of pyrethrum, dimefluthrin and meperfluthrin against Aedes aegypti and Aedes albopictus
2025LabWell-supported evidence
Laboratory fumigation and impregnated-paper bioassays of meperfluthrin against Aedes.
Paediatric lung injury due to accidental ingestion of meperfluthrin: a case report
2022Other
Single pediatric case report of accidental ingestion of a meperfluthrin liquid.
Vapor toxicity of five volatile pyrethroids against Aedes aegypti, Aedes albopictus, Culex quinquefasciatus, and Anopheles quadrimaculatus
2018LabLimited evidence
Laboratory vapor-toxicity ranking of five volatile pyrethroids against four mosquito species.
Evaluation of the acute toxicity of a mosquito coil based-meperfluthrin
2017Lab
Acute mammalian toxicity study of a meperfluthrin-based mosquito coil.

Products using it

Flextail

FLEXTAIL EVO Repeller

Prallethrin · Meperfluthrin

Coverage & effectiveness

Protected zone~15 ft zone

Fewer bitesest.40–65%

Flextail

FLEXTAIL Tiny Repeller S

Prallethrin · Meperfluthrin

Coverage & effectiveness

Protected zone~15 ft zone

Fewer bitesest.40–65%

Flextail

FLEXTAIL Max Repeller S

Prallethrin · Meperfluthrin

Coverage & effectiveness

Protected zone~15 ft zone

Fewer bitesest.40–65%

Flextail

FLEXTAIL Tiny Repel

Prallethrin · Meperfluthrin

Coverage & effectiveness

Protected zone~15 ft zone

Fewer bitesest.40–65%